n.BA.BT.PrBVT.22HS (Bioprocess Engineering Practical) 
Module: Bioprocess Engineering Practical
This information was generated on: 16 June 2024
Bioprocess Engineering Practical


Version: 2.0 start 01 August 2022


Study Programme Biotechnology
Regulations Applicable RPO, 29 January 2008, School of Life Sciences and Facility Management Academic Regulations, 15 Dec. 2009, Annex for the Bachelor of Biotechnology degree programme
Module Type  
X Compulsory Module    Elective Module    Optional Module
Planned Semester 3rd Semester
Module Coordinator Dieter Eibl
Telephone / E-Mail +41 (0)58 934 57 11 / dieter.eibl@zhaw.ch
Dieter Eibl and various lecturers
Entrance Requirements Introduction to Biotechnology, Industrial Systems 1 and 2, participation in Bioprocess Engineering 1
Learning Outcomes and Competencies Through the practicals, students will enhance their knowledge of working practices in process engineering and the most important basic operations of mechanical and thermal process engineering, as well as application thereof in biotechnology through calculation and design exercises and by means of practical work.
In the practical course, through calculation and design exercises as well as by means of practical tasks. students deepen their knowledge of process engineering working methods and the most important basic operations of mechanical and thermal process engineering and their applications in biotechnology.
Module Content The practicals include 4 blocks (below), the statistical design of experiments, the procedural design of a bioreactor system as well as mechanical and thermal reprocessing processes.
  1. Characterisation of coarse-disperse systems
    • Size reduction processes
    • Sieve analysis
    • Rheology
  2. Separation of biomass
    • Cake filtration
    • Depth filter
    • Crossflow
    • Centrifuge/Separator
    • Sedimentation
  3. Biomass digestion by means of
    • Ball milling
    • A high pressure homogenizer
    • Ultrasound
    • Enzymes
  4. Statistical exmperimental design and process characterisation, mass and heat exchange and design
    • Oxygen input
    • Mixing and residence time
    • Heat exchanger design
    • Agitator design
    • Bioreactor design
Follow-up Modules Bioprocess Engineering 2
Methods of Instruction  Tasks, SOPs, reports, presentations, independent self-study
Digital Resources Umetrics® suite MODDE
Lesson Structure / Workload  
 Contact Hours 52
 Guided Self-Study 6
 Independent Self-Study 32
 Total Workload 90
Classroom Attendance Exams (paper and electronic / e-assessment) and test protocols
Assessment Written assignment 100%

An exam must be passed before each practical. A protocol must be drawn up for each test and group.

Should a student fail this test, or fail to comply with the work and safety regulations, this will result in them not being allowed to continue with the practicals. In of the event of such an exclusion from the practicals, or any unexcused absences, a technical paper on the topic of the practicals (approx. 10 pages) must be written instead, which is then graded (Grade must be ≥ 4).
Language of Instruction  German
Comments The Bioprocess Engineering practical module is part of the module group Practicals 3


Practicals documents

Hemming, W., Verfahrenstechnik,Vogel, 2017
ISBN: 978-3-8343-3412-1

Ignatowitz, E., Chemietechnik, Verlag Europa-Lehrmittel, Haan-Gruiten, 2015
ISBN: 978-3-8085-7120-0

Schwister, K.; Leven, V., Verfahrenstechnik für Ingenieure,
Hanser Fachbuchverlag, 2020
ISBN: 978-3-446-46481-0

Storhas, W.
Bioverfahrensentwicklung,Wiley-VCH Verlag GmbH, 2013
ISBN: 978-3-527-32899-4

Vauck, W., R., A.; Müller, H., A.,Grundoperationen chemischer Verfahrenstechnik, Wiley-VCH Verlag, 1999
ISBN: 978-3-527-30964-1



  • This module description is due to be replaced by a new version as of 01 August 2024.
Course: Bioprocess Engineering Practical
Bioprocess Engineering Practical


  • No module description is available in the system for the cut-off date of 16 June 2024.