n.BA.BT.MB2I1.22HS (Molecular Biology 2 and Immunology 1) 
Module: Molecular Biology 2 and Immunology 1
This information was generated on: 30 November 2023
Molecular Biology 2 and Immunology 1


Version: 1.0 start 01 August 2022


Study Programme Biotechnology
Regulations Applicable RPO, 29 January 2008, School of Life Sciences and Facility Management Academic Regulations, 15 Dec. 2009, Annex for the Bachelor of Biotechnology degree programme
Module Type  
X Compulsory Module    Elective Module    Optional Module
Planned Semester 4th Semester
Module Coordinator Martin Sievers
Telephone / E-Mail +41 (0)58 934 57 16 / martin.sievers@zhaw.ch
Steffi Lehmann, Jack Rohrer
Entrance Requirements Molecular Biology 1, Cell Biology 1 and Cell Culture Technology 1, Pharmacology
Learning Outcomes and Competencies Students will be able to characterise the basics of the immune system and explain how an immune response is established, as well as how the innate and acquired aspects of the immune system interact. The roles and functions of the cells involved in the immune system can be explained with reference to the tissue involved.
Students will be able to describe the structure and function of antibodies in detail. They will be able to describe the functions of T cells and B cells, and explain the relationships of the interaction. They will be able to work out the strategy of how monoclonal antibodies are produced using hybridoma technology. Furthermore, they will be able to explain applications of antibodies in diagnostics and therapy as well as design concepts for the production of vaccines.
Module Content Overview of the human immune system: innate and acquired immune response. Responsible cells and organs of the immune system
Structure and composition of antibodies
Cell-mediated immune response by T cells, and the importance of B cells as producers of antibodies for the humoral immune response
Antigen processing and presentation through MHC class I and class II molecules
Activation of B cells as antigen-presenting cells through the type 2 T helper cells with the involvement of the corresponding cytokines
Hybridoma technology as a method for the production of a monoclonal antibody starting from an antigen
Applications of antibodies within diagnostics and treatments  
Overview of therapeutic antibodies
Overview of the different types of vaccines, together with examples
In-depth look at what happens during a vaccination reaction
Follow-up Modules Molecular Biology 3 and Immunology 2
Methods of Instruction  Lectures und tasks to complete
Digital Resources Video resources
Lesson Structure / Workload  
 Contact Hours 20
 Guided Self-Study 8
 Independent Self-Study 32
 Total Workload 60
Classroom Attendance No
Written exam at the end of the semester 100%
If there is a low number of participants, the lecturer may change the form of a repeat examination after consultation with the head of the study programme: e.g. an oral examination can be used to replace a written one. Please report any changes to the form of examinations by e-mail to pruefungsadmin.lsfm@zhaw.ch and Cc. Head of study programme
Language of Instruction  German
Comments Teaching materials:

PowerPoint slides from Molecular Biology 2 and Immunology 1 module.

Selection of books for further reading:

Cellular and Molecular Immunology, Abul K. Abbas, Andrew H. Lichtman, Elsevier, 10th edition (July 5, 2021)

Janeway, Immunology, by Kenneth Murphy, Casey Weaver, 2018 Springer Spektrum


Course: Molecular Biology 2 and Immunology 1
Molecular Biology 2 and Immunology 1


  • No module description is available in the system for the cut-off date of 30 November 2023.