n.BA.XX.MBDZB.23HS (Cell-based Bioanalysis) 
Module: Cell-based Bioanalysis
This information was generated on: 16 May 2024
No.
n.BA.XX.MBDZB.23HS
Title
Cell-based Bioanalysis
Credits
2

Description

Version: 2.0 start 01 August 2023

 

Study Programme Biotechnology / Chemistry
Regulations Applicable RPO vom 29. Januar 2008, Studienordnung des Dept. N vom 15. Dez. 2009, Anhang für den Bachelorstudiengang Biotechnologie

RPO vom 29. Januar 2008, Studienordnung des Dept. N vom 15. Dez. 2009, Anhang für den Bachelorstudiengang Chemie
Module Type  
X Compulsory Module    Elective Module    Optional Module
Planned Semester 5th Semester
Module Coordinator Prof. Dr. Sabina Gerber
Telephone / E-Mail +41 (0)58 934 54 28 / sabina.gerber@zhaw.ch
Lecturer(s),
Speaker(s),
Associate(s)		 Prof. Dr. Sabina Gerber and further lecturers
Entrance Requirements Fundamentals of Biochemistry and Bioanalytics
Learning Outcomes and Competencies Students will:
  • become familiar with detection methods for biomarkers such as metabolites, macromolecules and polymers within a cellular context
  • learn about detection methods for a wide range of substance classes from cells (proteomics, genomics, metabolomics, etc.)
  • become familiar with and apply analytical techniques for cells, their structures and organelles using imaging or optical methods in the context of biotechnological and biomedical questions
  • become familiar with and understand analysis methods for identifying cell types and cell surface structures, and assess various assay formats in terms of effort, complexity and informational content
  • become familiar with the fundamental approach and best practices in the computer-assisted analysis of data from cell-based analytical methods, including the potential of modern machine learning and AI-based methods
  • learn about the design and functional principles of biopharmaceutical testing systems based on cells and tissues, as well as understand their applications in preclinical R&D
  • become familiar with and understand the questions and bioanalytics of cell aggregates using histological methods
Module Content Cellular Bioanalytics:
  • State-of-the-art methods and devices for optically imaging and physically analysing cells and cell aggregates are explained in theory and experienced hands-on (including microscopy, fluorescence microscopy, electron microscopy, AFM, flow cytometry, in-situ microscopy, impedance spectroscopy, among others).
  • The interaction of proteins with living cells (including cell adhesion, uptake, intracellular trafficking, etc.) and methods for analytically tracking these processes are learned.
  • Transport experiments, migration assays, toxicity studies and other key concepts in pharmaceutical preclinical R&D are illustrated using practical examples.
  • Concepts of cellular diagnostics within the framework of biomedical investigations and treatment procedures (tissue engineering) are taught.
Follow-up Modules Biochemistry 4, Bachelor thesis
Methods of Instruction  Face-to-face teaching, practice tasks
Digital Resources All resources will be made available on Moodle:
  • Lecture slides
  • Practice tasks
Lesson Structure / Workload  
 Contact Hours 28
 Guided Self-Study -
 Independent Self-Study 32
 Total Workload 60
Classroom Attendance -
Assessment Written exam at the end of the semester 100%

For small groups, a separate module examination may also be conducted orally

If there is a low number of participants, the lecturer may change the form of a repeat examination after consultation with the head of the study programme: e.g. an oral examination can be used to replace a written one. Please report any changes to the form of examinations by e-mail to pruefungsadmin.lsfm@zhaw.ch and Cc. Head of study programme.
Language of Instruction  German
Comments -

 

Course: Cell-based Bioanalysis
No.
n.BA.XX.MBDZB.23HS.V
Title
Cell-based Bioanalysis

Note

  • No module description is available in the system for the cut-off date of 16 May 2024.