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n.BA.BT.BPT2.23HS (Bioprocess Technology 2)
Module: Bioprocess Technology 2
This information was generated on: 21 May 2024
No.
n.BA.BT.BPT2.23HS
Title
Bioprocess Technology 2
Credits
2
Description
Version: 1.0 start 01 August 2023
Study Programme
Biotechnology
Regulations Applicable
RPO, 29 January 2008, School of Life Sciences and Facility Management Academic Regulations, 15 Dec. 2009, Annex for the Bachelor of Biotechnology degree programme
Module Type
X
Compulsory Module
Elective Module
Optional Module
Planned Semester
5th Semester
Module Coordinator
Lukas Neutsch
Telephone / E-Mail
+41 (0)58 934 51 10 /
lukas.neutsch@zhaw.ch
Lecturer(s),
Speaker(s),
Associate(s)
Lukas Neutsch, Caspar Demuth and further internal and external lecturers.
Entrance Requirements
Practical Course Bioprocess Technology 1, Bioprocess Technology 1
Learning Outcomes and Competencies
Students will
expand their basic knowledge of biology, technology, analysis and balancing of industrial bioprocesses, and know how to apply this knowledge in practice
be able to independently perform calculations based on selected models of ideal reactor models.
They will learn about the most important concepts for:
Products and applications of intensified processes in biotechnology (pharmaceutical, chemical, cosmetics, food)
Design and process economics of industrial production facilities as a basis for decision-making on process strategies (batch vs fed-
batch vs continuous vs perfusion)
Biology, culture dynamics, methods and technology of controlled feed processes (fed
-batch) and continuous cultures
Cell retention systems, perfusion processes and cascade reactors
Interfaces to (semi-) continuous DSP operations
Computational design and model-based process planning/simulation
Process control types of continuous cultures (chemostat, turbidostat, nutristat)
Application and experimental design of continuous systems in strain characterisation and bioprocess optimis
ation
Integrated sensor and PAT concepts for bioprocess control
Cell-based analytical methods for characterisation of culture physiological parameters
Data-based evaluation (MVDA) of multiphase bioprocesses with online monitoring
Media development and optimisation for intensified processes (formulation / feed design)
Automated sampling and processing systems (robotics)
Industrially programmable process control systems
'Smart labs' & digital tools within bioprocess technology 4.0
Approval and regulatory classification of continuous processes
Students will also acquire theoretical background knowledge important for doing the ‘Biotechnological Internship’.
Module Content
The lecture build on basic knowledge in bioprocess technology, cell biology and process engineering, and extends students’ skillsets to include more complex, intensified production setups (in particular controlled feed processes, continuous bioprocesses, high cell density cultures). In addition to basic knowledge of methods, technical equipment and culture physiology of such bioprocesses, computational planning/design (incl. modelling) and data-based evaluation will be emphasised. Modern, integrated concepts of biotechnological production with fully automated systems, monitoring strategies and data management workflows put specific bioprocess knowledge into an overall context.
Follow-up Modules
Biotechnology Internship & Bioprocess Information Technology
Methods of Instruction
Lecture with calculation exercises
Digital Resources
-
Lesson Structure / Workload
Contact Hours
20
Guided Self-Study
18
Independent Self-Study
22
Total Workload
60
Classroom Attendance
Students must attend classes where the focus is on calculation exercises.
Assessment
Written exam at the end of the semester 50%
Coursework comprises various parts 50%: written and oral (participation, poster, handouts, calculation exercises)
If there is a low number of participants, the lecturer may change the form of a repeat examination after consultation with the head of the study programme: e.g. an oral examination can be used to replace a written one. Please report any changes to the form of examinations by e-mail to
pruefungsadmin.lsfm@zhaw.ch
and Cc. Head of study programme
Language of Instruction
German
Comments
-
Course: Bioprocess Technology 2
No.
n.BA.BT.BPT2.23HS.V
Title
Bioprocess Technology 2
Note
No module description is available in the system for the cut-off date of 21 May 2024.