n.BA.BT.BPT2.23HS (Bioprocess Technology 2) 
Module: Bioprocess Technology 2
This information was generated on: 21 May 2024
No.
n.BA.BT.BPT2.23HS
Title
Bioprocess Technology 2
Credits
2

Description

Version: 1.0 start 01 August 2023

 

Study Programme Biotechnology
Regulations Applicable RPO, 29 January 2008, School of Life Sciences and Facility Management Academic Regulations, 15 Dec. 2009, Annex for the Bachelor of Biotechnology degree programme
Module Type  
X Compulsory Module    Elective Module    Optional Module
Planned Semester 5th Semester
Module Coordinator Lukas Neutsch
Telephone / E-Mail +41 (0)58 934 51 10 / lukas.neutsch@zhaw.ch
Lecturer(s),
Speaker(s),
Associate(s)
Lukas Neutsch, Caspar Demuth and further internal and external lecturers.
Entrance Requirements Practical Course Bioprocess Technology 1, Bioprocess Technology 1
Learning Outcomes and Competencies Students will
  • expand their basic knowledge of biology, technology, analysis and balancing of industrial bioprocesses, and know how to apply this knowledge in practice
  • be able to independently perform calculations based on selected models of ideal reactor models.
 
They will learn about the most important concepts for:
  • Products and applications of intensified processes in biotechnology (pharmaceutical, chemical, cosmetics, food)
  • Design and process economics of industrial production facilities as a basis for decision-making on process strategies (batch vs fed-batch vs continuous vs perfusion)
  • Biology, culture dynamics, methods and technology of controlled feed processes (fed-batch) and continuous cultures
  • Cell retention systems, perfusion processes and cascade reactors
  • Interfaces to (semi-) continuous DSP operations
  • Computational design and model-based process planning/simulation
  • Process control types of continuous cultures (chemostat, turbidostat, nutristat)
  • Application and experimental design of continuous systems in strain characterisation and bioprocess optimisation
  • Integrated sensor and PAT concepts for bioprocess control
  • Cell-based analytical methods for characterisation of culture physiological parameters
  • Data-based evaluation (MVDA) of multiphase bioprocesses with online monitoring
  • Media development and optimisation for intensified processes (formulation / feed design)
  • Automated sampling and processing systems (robotics)
  • Industrially programmable process control systems
  • 'Smart labs' & digital tools within bioprocess technology 4.0
  • Approval and regulatory classification of continuous processes
 
Students will also acquire theoretical background knowledge important for doing the ‘Biotechnological Internship’.
Module Content The lecture build on basic knowledge in bioprocess technology, cell biology and process engineering, and extends students’ skillsets to include more complex, intensified production setups (in particular controlled feed processes, continuous bioprocesses, high cell density cultures). In addition to basic knowledge of methods, technical equipment and culture physiology of such bioprocesses, computational planning/design (incl. modelling) and data-based evaluation will be emphasised. Modern, integrated concepts of biotechnological production with fully automated systems, monitoring strategies and data management workflows put specific bioprocess knowledge into an overall context.
Follow-up Modules Biotechnology Internship & Bioprocess Information Technology
Methods of Instruction  Lecture with calculation exercises
Digital Resources -
Lesson Structure / Workload  
 Contact Hours 20
 Guided Self-Study 18
 Independent Self-Study 22
 Total Workload 60
Classroom Attendance Students must attend classes where the focus is on calculation exercises.
Assessment Written exam at the end of the semester 50%

Coursework comprises various parts 50%: written and oral (participation, poster, handouts, calculation exercises)

If there is a low number of participants, the lecturer may change the form of a repeat examination after consultation with the head of the study programme: e.g. an oral examination can be used to replace a written one. Please report any changes to the form of examinations by e-mail to pruefungsadmin.lsfm@zhaw.ch and Cc. Head of study programme
Language of Instruction  German
Comments -

 

Course: Bioprocess Technology 2
No.
n.BA.BT.BPT2.23HS.V
Title
Bioprocess Technology 2

Note

  • No module description is available in the system for the cut-off date of 21 May 2024.